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Outcomes are Worse in STEMI patients without CV risk factors

Miércoles, Julio 7, 2021

An analysis of Swedish registry data showed STEMI patients without cardiovascular risk factors — particularly women — experienced higher mortality.

Some patients who present with ST-segment elevation myocardial infarction (STEMI) do not have a history of standard modifiable cardiovascular risk factors (SMuRFs).

 

 
Código de aprobación: PP-CVP-GLB-0479

Blood Transfusion Strategy in Patients with Acute Myocardial Infarction

Martes, Junio 22, 2021

A randomized trial showed that a more-restrictive strategy was noninferior.

In previous large randomized trials, restrictive transfusion strategies benefited patients with anemia, but those trials excluded patients with acute myocardial infarction (MI)

 

 
Código de aprobación: PP-CVP-GLB-0470

Nonclassic TIA Symptoms and Stroke Risk

Martes, Junio 22, 2021

Both classic and nonclassic symptoms of transient ischemic attack confer similar 90-day stroke risk

The short-term risk for stroke after transient ischemic attack (TIA) is high, and urgent evaluation and treatment can reduce this risk

 

 
Código de aprobación: PP-CNS-GLB-1810

Can Antioxidants Affect Risk for Parkinson Disease?

Martes, Junio 22, 2021

Vitamins E and C may be associated with risk, but the evidence remains limited.

To determine whether risk for future Parkinson disease (PD) diagnosis was reduced with increased dietary antioxidant intake and total nonenzymatic antioxidant capacity (NEAC).

 

 
Código de aprobación: PP-CNS-GLB-1808

The Alzheimer Disease Conversion-Related Pattern Score as Neurodegeneration Biomarker

Miércoles, Junio 16, 2021

An ADCRP score may be useful in identifying those with mild cognitive impairment who have underlying Alzheimer disease.

To create a biological definition of Alzheimer disease (AD), the amyloid-tau-neurodegeneration (ATN) classification scheme has been developed.

 

 
Código de aprobación:PP-CNS-GLB-1779

Life expetancy after bariatric surgery

Martes, Junio 8, 2021

Obesity is associated with increases in life-threatening diseases and premature mortality.

Bariatric surgery leads to durable weight loss and reduces the risk for cardiovascular disease, type 2 diabetes, cancer, and all-cause death.

 

 
Código de aprobación: PP-IMU-GLB-0112

Scurvy Can Be Mistaken for Rheumatologic Disorders

Martes, Junio 1, 2021

Dietary vitamin C deficiency was identified in 10 patients previously suspected to have juvenile idiopathic arthritis, vasculitis, or chronic nonbacterial osteomyelitis.​

Scurvy is seldom suspected in children presenting with arthritis or extremity problems

 

 
Código de aprobación: PP-CVP-GLB-0455

Peripheral Nerve Stimulation for Tourette Syndrome

Martes, Junio 1, 2021

In the laboratory, median nerve stimulation reduced tic frequency and intensity and premonitory sensorimotor urges to tic.

Tourette syndrome (TS) is a neuropsychiatric disorder marked by involuntary tics, often associated with premonitory urges

 

 
Código de aprobación:PP-CNS-GLB-1780

Association Between Diet Quality, Cardiovascular Risk and Mortality Worldwide

Martes, Junio 1, 2021

Carbohydrate-containing foods and beverages have variable effects on health. So-called “poorcarbohydrate foods” have low amounts of fiber

It is broadly agreed that whole-grain and high-fiber foods help prevent chronic disease and that a diet with a low glycemic index helps with prevention and treatment of diabetes

 

 
Código de aprobación: PP-MHP-GLB-0201

A Randomized Trial of Focused-Ultrasound Subthalatomy for Parkinson Disease

Martes, Junio 1, 2021

Treatment resulted in more motor improvement than sham procedures but caused an unexpected number of adverse effects.

Focused ultrasound, an imaging-guided technique that can be used to create brain lesions, is FDA approved for use in thalamotomy to treat Parkinsonian tremors

 

 
Código de aprobación: PP-CNS-GLB-1779

Lung Cancer Screening

Martes, Junio 1, 2021

The Holy Grail in oncology is prevention against cancer ever occurring or detection early enough that curative treatment can be implemented.

 Lung cancer is the leading cause of cancer-related death

 

 
Código de aprobación: PP-IMU-GLB-0116

Is Cognitive-Behavioral Therapy an Option for Managing Knee Osteoarthritis?

Martes, Junio 1, 2021

CBT was inferior to pharmacological treatment in a randomized trial.

For patients with knee osteoarthritis (OA), nonsteroidal anti-inflammatory drugs (NSAIDs) are better than acetaminophen or placebo for achieving pain relief and improvement of function, so despite their known long-term risks,

 

 
Código de aprobación: PP-PPF-GLB-0380

Psychodynamic Psychotherapy for Functional Somatic Complaints

Martes, Junio 1, 2021

Short-term psychodynamic psychotherapy focusing on awareness and processing of emotionally laden material can be helpful for somatization.

Is psychodynamic psychotherapy still relevant? Researchers addressed this question in a meta-analysis of 17 randomized

 

 
Código de aprobación: PP-CNS-GLB-1778

Post-stroke Therapy and Prevention

Martes, Junio 1, 2021

Despite the fact that stroke is a leading cause of disability among adults, there has been a shortage of high-quality studies to address such important issues as management of stroke risk factors.

Well-documented risk factors include hypertension, diabetes mellitus, and hyperlipidemia.

 

 
Código de aprobación: PP-CVP-GLB-0454

Renal Ultrasound for Evaluating Asymptomatic Microscopic Hematuria

Martes, Junio 1, 2021

Ultrasound had very high sensitivity for identifying upper-tract cancer in this retrospective study

U.S. urology guidelines recommend computed tomographic (CT) urography to evaluate the upper urinary tract in patients with asymptomatic microscopic hematuria (J Urol 2012; 188:6 Suppl:2473).

 

 
Código de aprobación: PP-MHP-GLB-0200

Endovascular Thrombectomy for Acute Ischemic Stroke

Lunes, Mayo 31, 2021

Endovascular thrombectomy (EVT) has become an important treatment for patients with acute ischemic stroke who can be treated within 6 hours of stroke onset.

Select patients who meet certain imaging criteria can be treated up to 24 hours after stroke onset

 

 
Código de aprobación: PP-CNS-GLB-1777

Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest

Lunes, Mayo 31, 2021

Major advances in the care of cardiac arrest patients have been reported in the literature over the past decade

Ventilator-associated pneumonia (VAP) is common in the post-cardiac arrest period and requires additional resources for testing, therapies, and cost.

 

 
Código de aprobación: PP-IMU-GLB-0115

Hip Fracture Care: A step in the right direction

Lunes, Mayo 31, 2021

A quality-improvement intervention was associated with outcome successes. 

Fragility hip fractures, often caused by a fall from standing height, portend substantial morbidity and mortality.

 

 
Código de aprobación: PP-PPF-GLB-0379

Cardiovascular Risks During the Menopause Transition

Viernes, Mayo 28, 2021

This scientific statement provides a comprehensive review of the data linking the menopause transition to cardiovascular risk

The menopause transition (MT) occurs when menstrual cycles become variable or other menopauserelated symptoms begin and is separated into seven stages with varying duration, hormone levels, and symptoms

 

 
Código de aprobación: PP-CVP-GLB-0451

Is stroke risk in patients with Transient Ischemic Attack decreasing?

Viernes, Mayo 28, 2021

Data from the Framingham Study suggest that modern medical treatment helps.

Transient ischemic attacks (TIAs) are a well-recognized precursor to a potential ischemic stroke.

 

 
Código de aprobación: PP-CNS-GLB-1768

Prevalence of Pulmonary Embolism in Patients Admitted with COPD Exacerbations

Viernes, Mayo 28, 2021

A standardized screening algorithm detected PE in about 6% of hospitalized patients with chronic obstructive pulmonary disease.

Incidence of pulmonary embolism (PE) in patients who are hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) reportedly is as high as 16% (NEJM JW Emerg Med Oct 2016 and Chest 2017; 151:544).

 

 
Código de aprobación: PP-IMU-GLB-0111

Worldwide Trends in Cholesterol Levels

Jueves, Mayo 13, 2021

Almost 40 years of international data show that the highest mean non-HDL cholesterol levels shifted to East and Southeast Asia from high-income Western regions.

With the epidemiological transition (the movement toward noncommunicable disease with economic development), cardiovascular disease has emerged as a leading cause of death in countries with developing economies.

 

 
Código de aprobación: PP-CVP-GLB-0442

Intensity of Physical Activity and Risk for Death

Miércoles, Mayo 12, 2021

At least 150 minutes of physical activity weekly, with at least 75 minutes of vigorous activity, was best.

Among people who engage in the same amount of physical activity weekly, is vigorous physical activity (versus moderate activity) associated with lower risk for death?

 

 
Código de aprobación: PP-IMU-GLB-0098

DIAGNOSING AND PREDICTING DEVELOPMENT OF RHEUMATOID ARTHRITIS

Lunes, Marzo 29, 2021

The treatment of rheumatoid arthritis is fraught with unknowns.

It is not always certain how active the patient’s arthritis may be, even while they are engaged in an effective treatment regimen.

 

 
Código de aprobación: PP-PPF-GLB-0342

Determination of brain death

Lunes, Marzo 29, 2021

The first consensus recommendations on the topic aim to address variation in diagnosis at the international, national, and local levels.

Sponsoring Organization: World Brain Death Project, assisted by international professional societies including the World Federation of Intensive and Critical Care,

 

 
Código de aprobación: PP-CNS-GLB-1691

TOPIC COLLECTION: BENEFITS OF METABOLIC SURGERY

Lunes, Marzo 29, 2021

A plethora of studies comparing the metabolic benefits of bariatric surgery with usual medical management of obese patients has increased the focus on surgical management.

These studies initially focused on enhanced insulin sensitivity, improved glucose regulation, and a higher likelihood of reversing prediabetes and diabetes.

 

 
Código de aprobación: PP-IMU-GLB-0085

Can retinal thickness predict cognitive decline in PD

Lunes, Marzo 29, 2021

In a small study, two measures of retinal thickness showed greater thinning rates and correlations with cognitive decline in patients with PD than in controls.

Increasing interest has focused on the development of biomarkers capable of tracking Parkinson disease (PD) progression over time.

 

 
Código de aprobación: PP-UOP-GLB-0099

Association between migraine and cryptogenic stroke

Lunes, Marzo 29, 2021

A strong relationship was seen in both women and men, irrespective of the presence of PFO.

Previous studies have evaluated some of the complex relationships among cryptogenic stroke, migraine, and patent foramen ovale (PFO) and suggested the following:

 

 
Código de aprobación: PP-CNS-GLB-1694

Guidance in evaluation of microscopic hematuria

Lunes, Marzo 29, 2021

A new guideline recommends ultrasound instead of computed tomography for some patients with this finding.

How should we evaluate asymptomatic microscopic hematuria?

 

 
Código de aprobación: PP-MHP-GLB-0171

Amyloid burden - a reason for poor antidepressant response

Martes, Marzo 2, 2021

In cognitively intact individuals with late-life depression, cortical amyloid burden predicted poor antidepressant response.

Accumulation of cortical amyloid-β (Aβ) has been associated with greater depressive symptoms in cognitively intact older adults.

 

 
Código de aprobación: PP-CNS-GLB-1627

Safety and efficacy of extreme blood pressure lowering in ICH

Martes, Marzo 2, 2021

Higher rates of neurologic deterioration and adverse events were associated with intensive treatment in patients with excessively high initial systolic blood pressure.

Many patients with intracerebral hemorrhage (ICH) present with elevated systolic blood pressure (SBP). 

 

 
Código de aprobación: PP-CNS-GLB-1626

Psychiatric Disorders across the Lifespan- A Unitary Psychopathology Factor

Martes, Marzo 2, 2021

A 45-year longitudinal study shows that mental illness is astonishingly common and that it’s better to be a “lumper” than a “splitter” when thinking diagnostically.

Cross-sectional epidemiological surveys have documented high rates of lifetime psychiatric disorders (about 40%–50%) and substantial comorbidity.

 

 
Código de aprobación: PP-CNS-GLB-1625

PREVENTING SERIOUS FALL INJURIES

Martes, Marzo 2, 2021

TOPIC COLLECTION: PREVENTING SERIOUS FALL INJURIES​

About one in four older Americans fall each year, resulting in about 30,000 deaths and 800,000 hospitalizations annually. 

 

 
Código de aprobación: PP-PPF-GLB-0319

POEMS Syndrome

Martes, Marzo 2, 2021

A retrospective analysis of cases shows that smooth meningeal thickening provides an additional diagnostic clue differentiating POEMS syndrome from chronic immune demyelinating polyneuropathy.

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin lesions) is a rare but treatable paraneoplastic disorder of plasma cells associated with sensorimotor polyneuropathy.

 

 

 
Código de aprobación: PP-CNS-GLB-1624

Late-adult-onset idiopathic epilepsy and dementia risk

Lunes, Febrero 8, 2021

A large study of older veterans finds a nearly twofold increase in risk for dementia following diagnosis of late-onset seizures without known cause.

Do late-adult-onset seizures have an association with risk for dementia or just ref lect an independent cause without concern for a degenerative disease?

 

 
Código de aprobación: PP-CNS-GLB-1604

An Automated Web-Based Self-Help Program to Prevent Depression

Lunes, Febrero 8, 2021

Combining usual care with a guided program using cognitive-behavioral therapy reduced major depressive episodes by 52% in patients with chronic back pain.

Consistent with the move toward remote interventions for mental disorders, researchers assessed whether a web-based cognitive-behavioral therapy.

 

 
Código de aprobación: PP-CNS-GLB-1603

Adverse Pregnancy Outcomes Are Associated with Future Cardiovascular Risk

Lunes, Febrero 8, 2021

Hypertensive disorders of pregnancy and low birth weight carry the greatest risk.

Investigators have previously found an association between adverse pregnancy outcomes and future cardiovascular risk.

 

 
Código de aprobación: PP-CVP-GLB-0376

Aerobic Exercise, Cognition, and Cerebrovascular Regulation

Lunes, Febrero 8, 2021

Aerobic exercise improves cognitive, cardiovascular, and cerebrovascular outcomes in healthy older adults.

In this single-group intervention study, researchers examined the effects of aerobic exercise on cognition, cardiovascular fitness, and cerebrovascular regulation in 206 healthy adults

 

 
Código de aprobación: PP-CNS-GLB-1602

Psychodynamic Psychotherapy for Functional Somatic Complaints

Jueves, Enero 14, 2021

Short-term psychodynamic psychotherapy focusing on awareness and processing of emotionally laden material can be helpful for somatization.

Is psychodynamic psychotherapy still relevant? Researchers addressed this question in a meta-analysis of 17 randomized, controlled trials involving 2004 patients

 

 

 
Código de aprobación: PP-CNS-GLB-1595

An Easy Screen for Left Ventricular Dysfunction

Jueves, Enero 14, 2021

An algorithm developed with artificial intelligence was applied to electrocardiograms of patients presenting with dyspnea to the emergency department.

New articles about artificial intelligence–related decision-support tools are being published at a rapid pace.

 

 

 
Código de aprobación: PP-CVP-GLB-0370

Exercise-Induced Molecule Protects the Aging Brain

Jueves, Enero 14, 2021

The Gpld1 molecule seems to improve neurogenesis and cognition in mice.

In both animals and humans, regular exercise improves neurogenesis and cognition.

 

 

 
Código de aprobación: PP-CNS-GLB-1594

Intergenerational Transmission of Suicide

Miércoles, Enero 13, 2021

Risks for suicide attempts are strongly transmitted, with nature and nurture contributing equally, whereas the modest intergenerational transmission of completed suicide is largely genetic.​

Suicide attempts and suicides have long been known to run in families, but questions remain about the genetic versus environmental contributions to these phenomena.

 

 

 
Código de aprobación: PP-CNS-GLB-1598

Coronary disease risk score on CT

Miércoles, Enero 13, 2021

CT angiography might be useful to personalize decision-making about preventive therapies in low- or intermediate-risk patients.

Coronary computed tomography angiography (CCTA) can assess the degree and progression of coro-nary atherosclerosis and higher-risk plaque features, such as remodeling of the blood vessel wall, low attenuation lesions, and spotty calcification.

 

 

 
Código de aprobación: PP-CVP-GLB-0372

Risk Factors for Recurrent Transient Global Amnesia

Miércoles, Enero 13, 2021

Earlier age at first episode and personal or family history of migraine were associated with greater risk.

Transient global amnesia (TGA) is a benign but highly distressing event of antegrade amnesia that usually lasts a few hours.

 

 

 
Código de aprobación: PP-CNS-GLB-1597

Functional voice problems are more common in several chronic pain syndromes

Martes, Octubre 27, 2020

In a retrospective study, researchers examined associations between laryngeal disorders and fibromyalgia, irritable bowel, and chronic fatigue.

Fibromyalgia, irritable bowel, and chronic fatigue are syndromes that share chronic pain and other unexplained symptoms among their clinical manifestations. 

 

 

 
Código de aprobación: PP-PPF-ECU-0046

Delirium and Long-Term Cognitive Decline: Real Data

Martes, Octubre 27, 2020

Meta-analyses of studies of both surgical and nonsurgical patients confirm the long-suspected association.

Delirium is common in postoperative and critically ill hospitalized patients and has been estimated to occur in 25% of postsurgical patients and up to 82% of patients admitted to intensive care units.

 

 

 
Código de aprobación: PP-CNS-ECU-0094

What Happens After a First Episode of Postpartum Psychosis?

Martes, Octubre 27, 2020

A meta-analysis indicates that almost two thirds of women have another psychotic episode, predominantly outside the postpartum period.

Postpartum psychosis denotes a severe mood disorder episode having psychotic, manic, or mixed affective symptoms and occurring within the first few weeks after childbirth.

 

 

 
Código de aprobación: PP-CNS-ECU-0093

What Is the Natural History of Recent-Onset Monoarthritis?

Martes, Octubre 27, 2020

During 2 years of follow-up, most cases resolved, but one quarter developed into chronic inflammatory disease

The differential diagnosis of recent-onset monoarthritis is broad and includes early presentation of what eventually is identifiable as chronic inflammatory rheumatic disease (CIRD)

 

 

 
Código de aprobación: PP-PPF-ECU-0045

Peripheral Nerve Stimulation for Tourette Syndrome

Martes, Octubre 27, 2020

In the laboratory, median nerve stimulation reduced tic frequency and intensity and premonitory sensorimotor urges to tic.​

Tourette syndrome (TS) is a neuropsychiatric disorder marked by involuntary tics, often associated with premonitory urges.

 

 
Código de aprobación: PP-CNS-ECU-0092

Disrupted Structural Connectivity in Prefrontal Areas in Borderline Personality Disorder

Martes, Octubre 27, 2020

Disturbances are seen in white-matter structures responsible for the appropriate inhibition and control of emotions.

Many of the core features of borderline personality disorder (BPD; irritability, impulsivity, emotional instability) suggest disruption in frontolimbic brain circuits.

 

 

 
Código de aprobación: PP-CNS-ECU-0095

Predicting Cardiovascular Risks in a Contemporary Population

Martes, Octubre 27, 2020

The widely accepted pooled cohort equations overestimate 5-year risk in a cohort of Veterans Affairs patients, with implications for statin eligibility.

The pooled cohort equations (PCE) were developed to estimate the risk for an initial atherosclerotic cardiovascular disease (ASCVD) event. 

 

 

 
Código de aprobación: PP-CVP-ECU-0067

CSF Inflammatory Biomarkers of Multiple Sclerosis Disease Activity

Martes, Octubre 6, 2020

In a prospective 4-year study, more of those with elevated cytokine levels had evidence of disease activity.

Although multiple sclerosis (MS) is often considered a disease of the white matter, appreciation is growing that pathology also directly affects the cortex.

 

 

 
Código de aprobación: PP-CNS-ECU-0077

Associations Between Mental Disorders and Subsequent Medical Conditions

Martes, Octubre 6, 2020

Letter from the Editor

This collection (a seminal study from Denmark and several summaries of related studies along the medical-psychiatric interface) reminds us that the mind and body are continually interacting and affecting one another.

 

 

 

Código de aprobación: PP-CNS-ECU-0076

Implantable Cardiac Devices: Accessibility, Variability and Complications

Viernes, Octubre 2, 2020

Letter from the Editor

Access to medical care varies tremendously around the globe. It is especially in advanced technology that this variability exists, and particularly between underdeveloped and developed countries.

 

 

 

Código de aprobación:PP-CVP-ECU-0057

Neither Vigorous Activity nor Sedentary Behavior Is Associated with Risk for Knee Osteoarthritis

Viernes, Setiembre 18, 2020

Low-to-moderate physical activity might be protective.

Patients and some clinicians still are concerned that physical activity, particularly vigorous physical activity, might be associated with excess risk for knee osteoarthritis (OA), despite considerable evidence to the contrary.

 

 

 
Código de aprobación: PP-PPF-ECU-0034

New Insights and Future Directions in Parkinson's Disease

Viernes, Setiembre 18, 2020

Letter from the Editor

Clinicians and their patients with Parkinson disease await advances that will improve symptoms and quality of life. This year, we saw the emergence of several important clinical and research developments.

 

 

 

Código de aprobación: PP-CNS-ECU-0075

Plasma Biomarkers May Identify Risk for Dementia

Jueves, Setiembre 10, 2020

Plasma amyloid and neurofilament levels were associated with dementia risk in a population-based cohort.

Assessment of plasma biomarkers is emerging as a potential noninvasive way to determine risk for dementia.

 

 

 
Código de aprobación: PP-CNS-ECU-0066

Anxiety and Depression Can Make You Sick

Miércoles, Setiembre 2, 2020

Long-term associations between mental and physical health are examined in a prospective study.

To address the relationship between health and affective symptoms (anxiety or depression), researchers analyzed data from a British prospective study of 3001 people followed repeatedly since birth in 1946.

 

 

 
Código de aprobación: PP-CNS-ECU-0053

How Common Is ACS After Transcatheter Aortic-Valve Replacement?

Miércoles, Setiembre 2, 2020

Acute coronary syndrome is infrequent, presents most often as non-STEMI, but is associated with high early mortality.

Although as many as 50% of patients who undergo transcatheter aortic-valve replacement (TAVR) have known coronary artery disease, the incidence of acute coronary syndrome (ACS) after TAVR is unknown.

 

 

 
Código de aprobación: PP-CVP-ECU-0043

Pain Tolerability and the 10-Point Scale

Miércoles, Setiembre 2, 2020

A study suggests that asking about pain tolerability has advantages over using a 0-to-10–point numerical rating.

The common practice of asking patients to rate their pain on a 10-point scale might suggest that the goal of pain therapy always is to achieve a score of 0.

 

 

 
Código de aprobación: PP-PPF-ECU-0022

Connections Between the Ability to Cope with Stress and Tau Burden

Miércoles, Setiembre 2, 2020

Self-ratings of higher stress coping ability correlated with lower tau burden on brain scans in older adults.

The relationship between psychological stress and neurodegenerative syndromes has been established clinically.

 

 

 
Código de aprobación: PP-CNS-ECU-0052

Topic Collection: MRI with biopsy for prostate cancer diagnosis - Part I

Miércoles, Setiembre 2, 2020

Letter from the Editor

The late Dr. Willet Whitmore, long-serving Chair of Urology at Memorial Sloan Kettering Cancer Center, noted in his 1973 treatise on the natural history of prostate cancer that “Appropriate treatment implies that therapy be applied neither to those patients for whom it is unnecessary nor to those for whom it will prove ineffective.”

 

 

 

Código de aprobación: PP-MHP-ECU-0030

 

Hearing Voices in Patients with Trauma

Lunes, Agosto 24, 2020

Auditory hallucinations are common in women with severe PTSD, especially among those who were younger at the initial trauma.

Clinically, auditory hallucinations are most often linked to psychotic disorders, such as schizophrenia, severe bipolar disorders, drug-induced psychoses, and neurodegenerative diseases.

 

 

 
Código de aprobación: PP-CNS-ECU-0051

Remote Telehealth Is Noninferior to In-Person Home-Based

Lunes, Agosto 24, 2020

Remote sessions might become a convenient alternative to traveling for face-to-face care.

Telehealth programs are both cost-effective and more convenient alternatives to in-person interventions in people with dementia, especially as the dementia progresses.

 

 

 
Código de aprobación: PP-CNS-ECU-0050

Mycoplasma genitalium Urethritis: Prevalence and Drug-Resistance Patterns

Lunes, Agosto 24, 2020

Persistent urethritis symptoms are frequent in men regardless of the detection of M. genitalium.

Mycoplasma genitalium (MG) is increasingly recognized as a cause of male urethritis, and recent studies indicate increasing prevalence of macrolide-resistance mutations (MRMs).

 

 

 
Código de aprobación: PP-MHP-ECU-0024

Impact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes- a rapid evidence assessment of recent literature

Martes, Mayo 26, 2020

The 2018 European Society of Cardiology/ European Society of Hypertension Guidelines for the management of arterial hypertension raised the need for evidence to support the use of single-pill combination (SPC) therapy in preference to free-dosed therapy for hypertension. This systematic rapid evidence assessment sought to determine if initiating SPC therapy improves adherence, blood pressure (BP) control and/or cardiovascular outcomes vs. initiation of free-dose combination therapy.

 

 

 
 
Código de aprobación: PP-CVP-ECU-0022

Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation. NEJM Journal Watch summary, reused with permission from NEJM Group

Jueves, Marzo 19, 2020

Optical sensors on wearable devices can detect irregular pulses. The ability of a smartwatch application (app) to identify atrial fibrillation during typical use is unknown.
Participants without atrial fibrillation (as reported by the participants themselves) used a smartphone (Apple iPhone) app to consent to monitoring. If a smartwatchbased irregular pulse notification algorithm identified possible atrial fibrillation, a telemedicine visit was initiated and an electrocardiography (ECG) patch was mailed to the participant, to be worn for up to 7 days.

 

 
Código de aprobación: